Periodicals Collection Management: Organizing, Creating, and Maintaining a System

This paper examines Providence College’s experience in organizing, creating, and implementing the library’s collection management system, including how and why we chose Microsoft Access®, involved non-periodicals library staff in each phase, worked with existing periodicals information to form the basis for the collection management system, decided which information/fields to include, and retrieved/compiled the necessary information about each title by comparing our existing records to what was physically on the shelf. We also discuss how we used the collection management system to solicit input into collection management decisions such as cancellations and retention, create detailed reports with a variety of information, provide the information required for the periodicals integration project that combined the previously separate humanities and science collections into one collection as part of the library renovation project, manage the temporary division of the collection into three locations as part of the library renovation project, and assist academic departments in managing periodical titles in their respective areas

Periodicals Collection Management: Organizing, Creating, and Maintaining a System (As published)

This paper examines Providence College’s experience in organizing, creating, and implementing the library’s collection management system, including how and why we chose Microsoft Access®, involved non-periodicals library staff in each phase, worked with existing periodicals information to form the basis for the collection management system, decided which information/fields to include, and retrieved/compiled the necessary information about each title by comparing our existing records to what was physically on the shelf.We also discuss how we used the collection management system to solicit input into collection management decisions such as cancellations and retention, create detailed reports with a variety of information, provide the information required for the periodicals integration project that combined the previously separate humanities and science collections into one collection as part of the library renovation project, manage the temporary division of the collection into three locations as part of the library renovation project, and assist academic departments in managing periodical titles in their respective areas

N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods

Metastasizing tumor cells use matrix metalloproteases, such as the transmembrane collagenase MT1-MMP, together with actin-based protrusions, to break through extracellular matrix barriers and migrate in dense matrix. Here we show that the actin nucleation–promoting protein N-WASP (Neural Wiskott-Aldrich syndrome protein) is up-regulated in breast cancer, and has a pivotal role in mediating the assembly of elongated pseudopodia that are instrumental in matrix degradation. Although a role for N-WASP in invadopodia was known, we now show how N-WASP regulates invasive protrusion in 3D matrices. In actively invading cells, N-WASP promoted trafficking of MT1-MMP into invasive pseudopodia, primarily from late endosomes, from which it was delivered to the plasma membrane. Upon MT1-MMP’s arrival at the plasma membrane in pseudopodia, N-WASP stabilized MT1-MMP via direct tethering of its cytoplasmic tail to F-actin. Thus, N-WASP is crucial for extension of invasive pseudopods into which MT1-MMP traffics and for providing the correct cytoskeletal framework to couple matrix remodeling with protrusive invasion